The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 11, 2005

Filed:

Nov. 28, 2001
Applicants:

Rina K. Dukor, Lake Zurich, IL (US);

Curtis A. Marcott, Cincinnati, OH (US);

Inventors:

Rina K. Dukor, Lake Zurich, IL (US);

Curtis A. Marcott, Cincinnati, OH (US);

Assignees:

Vysis, Inc., Downers Grove, IL (US);

Procter & Gamble, Cincinnati, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 2162 ;
U.S. Cl.
CPC ...
Abstract

A method and system for diagnosing pathology, such as carcinoma, in a biological sample identifies presence of pathology based on the existence of an infrared markers in the extracellular material, rather than cells, in the biological sample. In the case of breast cancer diagnosis, an effective marker is a baseline slope of a 1280 cmband in the infrared spectra of connective tissue, with normal biopsy samples exhibiting a positive slope and cancerous samples showing a relatively flat baseline. Infrared spectroscopy, both microscopic and macroscopic, may be used to identify a sample region containing extracellular material and to collect infrared absorbance data, from which the existence of the pathology marker is determined.


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