The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6841371 B1

PDF
Full Text
Expired
Date of Patent:
Jan. 11, 2005

Filed:

Jan. 19, 2001
Applicants:

Bruce Edward Gerlitz, Indianapolis, IN (US);

Bryan Edward Jones, Carmel, IN (US);

Inventors:

Bruce Edward Gerlitz, Indianapolis, IN (US);

Bryan Edward Jones, Carmel, IN (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 964 ; A01N 6100 ; A01N 2500 ; A61K 3828 ; A61K 3500 ; A61K 3514 ;
U.S. Cl.
CPC ...
Abstract

Novel human protein C derivatives are described. These derivatives have increased anti-coagulation activity and resistance to inactivation by serpins, compared to wild-type protein C and retain the biological activity of the wild-type human protein D. These derivatives will require either less frequent administration and/or smaller dosage than wild-type human protein C in the treatment of acute coronary syndromes, vascular occlusive disorders, hyper coagulable states, thrombotic disorders and disease states predisposing to thrombosis.


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