The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 04, 2005
Filed:
May. 06, 2002
Timothy Allen Blizzard, Middletown, NJ (US);
Milton Lloyd Hammond, Somerville, NJ (US);
Jerry Dwain Morgan, Sayreville, NJ (US);
Ralph Troy Mosley, Roselle, NJ (US);
Timothy Allen Blizzard, Middletown, NJ (US);
Milton Lloyd Hammond, Somerville, NJ (US);
Jerry Dwain Morgan, Sayreville, NJ (US);
Ralph Troy Mosley, Roselle, NJ (US);
Merck & Co., Inc., Rahway, NJ (US);
Abstract
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a variety of conditions related to estrogen functioning including: bone loss, bone fractures, osteoporosis, cartilage degeneration, endometriosis, uterine fibroid disease, hot flashes, increased levels of LDL cholesterol, cardiovascular disease, impairment of cognitive functioning, cerebral degenerative disorders, restenosis, gynecomastia, vascular smooth muscle cell proliferation, obesity, incontinence, and cancer, in particular of the breast, uterus and prostate.