The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 04, 2005
Filed:
Sep. 25, 1998
Jeroen Krijgsveld, Amsterdam, NL;
Sebastianus Antonius Johannes Zaat, Amstelveen, NL;
Jacob Dankert, Baambrugge, NL;
Alma Johanna Kuijpers, Enschede, NL;
Gerardus Henricus Maria Engbers, Oldenzaal, NL;
Jan Feijen, Hengelo, NL;
Jeroen Krijgsveld, Amsterdam, NL;
Sebastianus Antonius Johannes Zaat, Amstelveen, NL;
Jacob Dankert, Baambrugge, NL;
Alma Johanna Kuijpers, Enschede, NL;
Gerardus Henricus Maria Engbers, Oldenzaal, NL;
Jan Feijen, Hengelo, NL;
Abstract
The present invention relates to isolated and recombinant antimicrobial peptides thrombocidin-1 (TC-1) and thrombocidin-2 (TC-2), or variants thereof, which comprise at least in part the sequence as shown in FIG.indicated by the label TC-1 and TC-2, and have antimicrobial activity against gram-positive and gram-negative bacteria, for example, and, and/or against fungi, for example, andspec. The invention further relates to the use of said peptides, or variants thereof, for the preparation of a medicament for the treatment of bacterial or fungal infections, such as endocarditis, in humans and animals and the use of said peptides, or variants thereof, in release systems for prevention of bacterial or fungal infections in humans and animals.