The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 04, 2005
Filed:
Dec. 15, 1993
David B. Weiner, Merion, PA (US);
David Nathan Levy, Philadelphia, PA (US);
Yosef Refaeli, Philadelphia, PA (US);
David B. Weiner, Merion, PA (US);
David Nathan Levy, Philadelphia, PA (US);
Yosef Refaeli, Philadelphia, PA (US);
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
The Wistar Institute, Philadelphia, PA (US);
Abstract
Pharmaceutical compositions comprising the HIV protein vpr or nucleic acid molecule encoding vpr are disclosed. Also disclosed are methods of treating patients suffering from diseases characterized by hyperproliferating undifferentiated cells such as cancer by administering such compositions. Methods of identifying compounds which have anti-HIV activity are disclosed, in particular, methods of identifying compounds which modulate the activity of vpr and of identifying compounds which inhibit vpr binding to the HIV protein gag.