The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 28, 2004
Filed:
Jun. 08, 2001
Applicant:
Inventor:
Ulf Smith, Vallda, SE;
Assignee:
Metcon Medicin AB, Lidingo, SE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 1/900 ; C07H 2/102 ; C12P 2/106 ;
U.S. Cl.
CPC ...
C07H 1/900 ; C07H 2/102 ; C12P 2/106 ;
Abstract
Novel non-coding sequences isolated upstream of the human IRS-2 gene are disclosed as markers for the prediction and/or diagnosis of IRS-2 related metabolic disorders or diseases, such as diabetes. The sequences also fuction as markers in a method and assay for evaluating the insulin regulating, i.e. insulin sensitizing or inhibiting properties of drug candidate substances, e.g. a method and assay for high throughput screening. The sequences and/or information derived therefrom can also be used for influencing the expression of the IRS-2 gene, e.g. in the therapy of IRS-2 related metabolic disorders, such as diabetes.