The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 21, 2004
Filed:
Sep. 04, 2003
Yuri Osipchuk, Foster City, CA (US);
Sasha Dromaretsky, Davis, CA (US);
Yuriy Roll, Foster City, CA (US);
Stephen Smith, Los Altos, CA (US);
Axon Instruments, Inc., Foster City, CA (US);
Abstract
A fluorescent optical imaging system ( ) produces two separate spots (S and S ) on a sample ( ) by a pair of excitation laser beams (B and B ) that are generated by first and second lasers (L and L ). Excitation laser beams (B and B ) pass at slightly different angles, first through an aperture ( ) of a 45° fold mirror ( ), and then through an objective element ( ). As a result, emission light beams ( ) are generated from each illuminated spot (S and S ) and are reflected and redirected by mirror ( ) through a secondary lens ( ) before reaching one of two detectors (PMT and PMT ). Emission beam ( ) reflects off a second 45° mirror ( ) prior to reaching detector (PMT ), while emission beam ( ) travels directly to (PMT ). If desired, optical separation elements ( ), such as dichroic filters, prisms, or gratings, can be positioned in front of each detector (PMT and PMT ). Fluorescent optical imaging system ( ) may employ a scanning system ( ) for illuminating and imaging the entire area of sample ( ).