The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 21, 2004
Filed:
Jun. 28, 2001
Applicant:
Inventors:
Assignee:
Ajinomoto Co., Inc., Tokyo, JP;
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/10 ; A61K 3/845 ; A23J 3/20 ;
U.S. Cl.
CPC ...
C12N 9/10 ; A61K 3/845 ; A23J 3/20 ;
Abstract
The present invention relates to a high-yield process for producing high-activity, high-purity transglutaminase by refolding denatured microorganism-derived transglutaminase by reacting denatured transglutaminase in an aqueous medium under acidic conditions and reconstituting a higher-order enzymatically active state in an aqueous medium at a neutral pH.