The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 14, 2004
Filed:
Dec. 09, 2002
Applicant:
Inventors:
Jörg Stürzebecher, Erfurt, DE;
Torsten Steinmetzer, Jena, DE;
Andrea Schweinitz, Jena, DE;
Assignee:
Curacyte AG, Munich, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; A61K 3/116 ;
U.S. Cl.
CPC ...
C07C / ; A61K 3/116 ;
Abstract
The invention relates to a highly active, highly specific urokinase inhibitor which is suitable for therapeutic applications and can be synthesized in an extremely simple manner. Surprisingly, it was found that amidino benzylamine derivatives, especially 4-amidino-benzylamine, with two bonded amino acids represent a new group of highly active and very selective uPA inhibitors. The urokinase inhibitors can be used in medical applications, e.g. in the treatment of malign tumors such as in cases of metastatic spread.