The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 14, 2004
Filed:
Sep. 21, 2000
Applicant:
Inventors:
Peter S. Linsley, Seattle, WA (US);
Jeffrey A. Ledbetter, Seattle, WA (US);
Nitin K. Damle, Renton, WA (US);
William Brady, Bothell, WA (US);
Assignee:
Bristol-Myers Squibb Company, Princeton, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 3/353 ;
U.S. Cl.
CPC ...
G01N 3/353 ;
Abstract
The invention provides a method for generating and identifying antibodies directed against a B7 antigen having SEQ ID NO. 8 or a fragment of SEQ ID NO. 8, which antibodies inhibit B cells from binding CD28, comprising immunizing an animal with the B7 antigen so as to produce the antibodies; and screening the antibodies for antibodies that bind B7 and inhibit CD28 binding to B cells.