The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 14, 2004
Filed:
Oct. 18, 2001
Applicant:
Inventor:
Yasutaka Shimokawatoko, Kobe, JP;
Assignee:
Sumotimo Chemical Company Limited, Osaka, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/02 ; C12N 1/500 ; C12N 5/00 ; C12N 1/574 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12N 9/02 ; C12N 1/500 ; C12N 5/00 ; C12N 1/574 ; C07H 2/104 ;
Abstract
The present invention provides a method for evaluating the ability of a compound to inhibit protoporphyrinogen oxidase activity, which comprises the steps of (1) culturing a transformant expressing a heterologous protoporphyrinogen oxidase (PPO) gene in a medium containing substantially no protoheme compounds in the presence and absence of a test compound to measure the growth rate of the transformant, wherein the transformant is a host cell deficient in PPO activity which is transformed with the heterologous PPO gene, and (2) determining the ability of the compound to inhibit the protoporphyrinogen oxidase activity by comparing growth rates.