The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 07, 2004
Filed:
Oct. 16, 2002
Applicant:
Inventors:
David A. Stein, Corvallis, OR (US);
Douglas E. Skilling, Corvallis, OR (US);
Patrick L. Iversen, Corvallis, OR (US);
Alvin W. Smith, Corvallis, OR (US);
Assignee:
AVI BioPharma, Inc., Corvallis, OR (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 ; C12P 1/934 ; A01N 4/304 ; C07H 2/102 ; C07H 2/100 ;
U.S. Cl.
CPC ...
C12Q 1/68 ; C12P 1/934 ; A01N 4/304 ; C07H 2/102 ; C07H 2/100 ;
Abstract
The invention provides antisense antiviral compounds and methods of their use in inhibition of growth of viruses of the picornavirus, calicivirus, togavirus and flavivirus families, as in treatment of a viral infection. The antisense antiviral compounds are substantially uncharged oligomers having a targeting base sequence that is substantially complementary to a viral target sequence which spans the AUG start site of the first open reading frame of the viral genome.