The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 07, 2004

Filed:

Jun. 13, 2003
Applicant:
Inventor:

Klaus W. Berndt, Timonium, MD (US);

Assignee:

Becton, Dickinson and Company, Franklin Lakes, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/00 ; G01N 3/300 ; B01L 3/00 ; B01L 9/00 ;
U.S. Cl.
CPC ...
G01N 1/00 ; G01N 3/300 ; B01L 3/00 ; B01L 9/00 ;
Abstract

A liquid sample sensing device comprises a set of stackable liquid sample base units that are adapted to be stacked together to form multiple sample volumes that are substantially sealed, each with an electroacoustic member disposed therein having a surface adapted for binding to a particular target molecule. Top and bottom units are preferably attached to a closed loop of flexible tubing and a peristaltic pump. Individual electroacoustic members in the stack can each be adapted to bind with different target molecules, allowing for a multiple target assay. Alternately, a plurality of electroacoustic members can be adapted to bind with the same type of target molecule, thereby increasing the sensitivity of the sensing device. The base units are adapted such that sample liquid is caused to flow over and be in close proximity to the sensing surface of each electroacoustic member as the sample liquid flows from one base unit to the next, thereby increasing the efficiency of binding.


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