The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 23, 2004

Filed:

Jun. 27, 2001
Applicant:
Inventors:

Keisuke Furukawa, Chiba, JP;

Yasuji Koyama, Chiba, JP;

Masaru Suzuki, Chiba, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/14 ; C12N 9/78 ;
U.S. Cl.
CPC ...
C12N 9/14 ; C12N 9/78 ;
Abstract

The present invention relates to a thermostable creatine amidinohydrolase having the following physicochemical properties: (a) hydrolyzing 1 mol of creatine to give 1 mol of sarcosine and 1 mol of urea; (b) having a substrate specificity to creatine; (c) having an optimum pH of 7.0 to 8.0; (d) having a stable pH range of 4.0 to 11.0; (e) having the optimum temperature of around 45° C.; (f) being thermostable at 53° C.; (g) having a molecular weight of 92,000 Da (as determined by gel filtration), and to a process for producing the thermostable creatine aimdinohydrolase.


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