The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2004
Filed:
Apr. 17, 1998
Applicant:
Inventors:
Sam D. Sanderson, Omaha, NE (US);
Michael A. Hollingsworth, Omaha, NE (US);
Richard A. Tempero, Omaha, NE (US);
Assignee:
The Board of Regents of the University of Nebraska, Lincoln, NE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/900 ; A61K 3/939 ; C07K 1/400 ;
U.S. Cl.
CPC ...
A61K 3/900 ; A61K 3/939 ; C07K 1/400 ;
Abstract
Molecular adjuvants are disclosed comprising an antigen presenting cell-targeting ligand functionally linked to an immunogen, e.g. tumor associated antigens, bacterial or viral antigens, etc. Methods are disclosed for delivery of these molecular adjuvants to patients, resulting in the transduction of activating signals to the targeted antigen presenting cell, thereby enhancing the immune response to the co-delivered immunogen.