The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 16, 2004
Filed:
Feb. 07, 2000
Applicant:
Inventors:
Stefan Niewiarowski, Narbeth, PA (US);
Cezary Marcinkiewicz, Philadelphia, PA (US);
Assignee:
Temple University- Of The Commonwealth System of Higher Education, Philadelphia, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/816 ; C07K 1/446 ;
U.S. Cl.
CPC ...
A61K 3/816 ; C07K 1/446 ;
Abstract
This invention relates to the identification, purification, and characterization of a novel heterodimeric disintegrin, EC-3, from viper venom. EC-3 inhibits &agr;4 integrins in an RGD-independent manner. The invention further relates to methods of using EC-3, or a biologically active fragment or derivative thereof, to inhibit the interaction between cells expressing &agr;4 integrins and cellular ligands.