The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 16, 2004

Filed:

Nov. 22, 2000
Applicant:
Inventors:

Kyriacos A. Mitrophanous, Oxford, GB;

Deva Patil, Oxford, GB;

Alan J. Kingsman, Oxford, GB;

Susan M. Kingsman, Oxford, GB;

Fiona M. Ellard, Oxford, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 4/800 ; C12N 1/5867 ; C12N 1/563 ; C12N 1/564 ;
U.S. Cl.
CPC ...
A61K 4/800 ; C12N 1/5867 ; C12N 1/563 ; C12N 1/564 ;
Abstract

A retroviral delivery system capable of transducing a target site is described. The retroviral delivery system comprises a first nucleotide sequence coding for at least a part of an envelope protein; and one or more other nucleotide sequences derivable from a retrovirus that ensure transduction of the target site by the retroviral delivery system; wherein the first nucleotide sequence is heterologous with respect to at least one of the other nucleotide sequences; and wherein the first nucleotide sequence codes for at least a part of a rabies G protein or a mutant, variant, derivative or fragment thereof that is capable or recognising the target site.


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