The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 09, 2004

Filed:

Sep. 23, 2003
Applicant:
Inventors:

Philip Anthony Harris, Durham, NC (US);

Lee Frederick Kuyper, Durham, NC (US);

Karen Elizabeth Lackey, Durham, NC (US);

James Marvin Veal, Durham, NC (US);

Assignee:

SmithKline Beecham Corporation, Philadelphia, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/133 ; A61K 3/1407 ; A61K 3/138 ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/133 ; A61K 3/1407 ; A61K 3/138 ; C07D / ; C07D / ;
Abstract

Substituted aza-oxindole derivatives useful as cyclin dependent kinase II inhibitors, for preventing/reducing the severity of epithelial cytotoxicity side-effects (e.g., alopecia, plantar-palmar syndrome, mucositis) induced by chemoptherapy and/or radiation therapy in a patient receiving such therapy.


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