The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 09, 2004
Filed:
Aug. 17, 2001
Applicant:
Inventors:
Daniel R. Twardzik, Bainbridge Island, WA (US);
Andre Pernet, Lake Forest, IL (US);
Thomas S. Felker, Vashon, WA (US);
Stefan Paskell, Bainbridge Island, WA (US);
Assignee:
Kaleidos Pharma, Inc., Seattle, WA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/818 ; C07K 1/4495 ;
U.S. Cl.
CPC ...
A61K 3/818 ; C07K 1/4495 ;
Abstract
Disclosed are TGF-&agr; polypeptides, related polypeptides, fragments and mimetics thereof useful in stimulating stem cell or precursor cell proliferation, migration and differentiation. The methods of the invention are useful to treat tissue injury as well as expand stem cell populations in, or obtained from, gastrointestinal, musculoskeletal, urogenital, neurological and cardiovascular tissues. The methods include ex vivo and in vivo applications.