The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 09, 2004
Filed:
Dec. 28, 2001
Applicant:
Inventors:
Jim P. Boyce, Kirkland, WA (US);
J. Jeffry Howbert, Bellevue, WA (US);
John C. Tabone, Bothell, WA (US);
Assignee:
Celltech R & D, Inc., Slough, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 2/400 ; G01N 3/3534 ; A61K 3/1498 ; C07D / ;
U.S. Cl.
CPC ...
G01N 2/400 ; G01N 3/3534 ; A61K 3/1498 ; C07D / ;
Abstract
The synthesis of novel diketopiperazines, their use in inhibiting cellular events such as those involving NFK-&agr;, NFK-&bgr; and in the treatment of inflammation events, a combinatorial library of diverse diketopiperazines and process for their synthesis as a library and as individual compounds. In particular novel diketopiperazines are disclosed including their synthesis and use in cellular events such as activation of the transcription factor, nuclear factor, TNF-&agr;, TNF-&bgr; and also apoptosis.