The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 09, 2004
Filed:
Nov. 21, 2001
George S. Wilson, Lawrence, KS (US);
Xiaohong Chen, Lawrence, KS (US);
Norio Matsumoto, Matsudo Chiba, JP;
Yibai Hu, Lawrence, KS (US);
University of Kansas, Lawrence, KS (US);
Abstract
Improved biosensors are provided having excellent selectivity and stability properties, together with methods of preparing the biosensors. A preferred biosensor includes an electrode ( ) having enzyme ( ) deposited thereon together with a layer of electropolymerized polymer ( ) intermingled with the enzyme ( ); a crosslinked silane film ( ) is applied over the polymer layer ( ), and a final coating ( ) of polyurethane is formed over the film ( ). In preparative procedures, the enzyme ( ) is electrodeposited using an aqueous enzyme solution containing a nonionic surfactant at a concentration level preferably in excess of the critical micelle concentration of the surfactant. In the case of a glucose sensor, the polymer layer ( ) is preferably polyphenol, while the silane film is crosslinked (3-aminopropyl) trimethoxysilane. The preferred biosensors have greatly enhanced selectivity stabilities.