The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2004
Filed:
Jul. 24, 2002
Sekar Alla, Greensboro, NC (US);
Seung-Yong Choi, Greensboro, NC (US);
Dale Dhanoa, Wakefield, MA (US);
Elso DiFranco, Greensboro, NC (US);
Galina Krokhina, Greensboro, NC (US);
Keqiang Li, Greensboro, NC (US);
Balasubramanian Thiagarajan, Raleigh, NC (US);
Wen-Chun Zhang, Greensboro, NC (US);
PharmaCore, Inc., High Point, NC (US);
Abstract
The present invention provides certain alpha-amino acids and derivatives thereof, such as, but not limited to, esters, amides and salts. These derivatives may comprise such representative side groups as a phenyl, pyridyl, piperidinyl, tetrahydropyranyl, tetrahydrothiopyranyl, or thienyl group. The present invention further provides a method for synthesizing alpha-amino acids and derivatives thereof via a modified Ugi type reaction using an aldehyde, ammonium formate and a C -C alkyl isocyanide. The compounds provided by this method are useful in the development of new pharmaceuticals for the treatment of human diseases.