The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2004
Filed:
Dec. 06, 2001
Applicant:
Inventors:
John P. Morseman, Columbia, MD (US);
Xiangfei Zeng, Beaverton, OR (US);
Assignee:
Martek Biosciences Corporation, Columbia, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/04 ; C07K 1/13 ; C12N 9/96 ; C12N 1/106 ; C12N 1/112 ;
U.S. Cl.
CPC ...
C07K 1/04 ; C07K 1/13 ; C12N 9/96 ; C12N 1/106 ; C12N 1/112 ;
Abstract
The present invention relates to methods for coupling labels to particular target moieties. The coupling reactions of the present invention use temporal spacing of the reactants through phase change (i.e. by rapid freezing) to control the initiation and termination of reaction. This process results in a simplified and improved method for linking labels to specific binding moieties using N-hydroxysuccinimide chemistry. The present invention further relates to kits comprising all necessary components to easily and rapidly make protein conjugates.