The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2004
Filed:
Mar. 29, 2001
Applicant:
Inventors:
Triptikumar Mukhopadhyay, Mumbai, IN;
Kenia Jayvanti, Mumbai, IN;
Erra Koteswara Satya Vijaya Kumar, Mumbai, IN;
Assignee:
Aventis Pharma Deutschland GmbH., Frankfurt, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/812 ; A61K 3/800 ; C07K 7/00 ; C12P 2/104 ;
U.S. Cl.
CPC ...
A61K 3/812 ; A61K 3/800 ; C07K 7/00 ; C12P 2/104 ;
Abstract
The invention relates to a process for the conversion of echinocandin class of peptides to their C4-homotyrosine monodeoxy analogues, particularly mulundocandin to deoxymulundocandin, which consists of a single step selective reduction of C4-htyr (homotyrosine) hydroxyl group of echinocandins to their monodeoxy analogues under neutral conditions without prior protection/deprotection of the equally facile C5-Orn (ornithine) hydroxyl group and purification of the monodeoxy compound from the crude reaction mixture.