The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2004
Filed:
Dec. 16, 1998
Applicant:
Inventors:
Ethan Bier, San Diego, CA (US);
Kweon Yu, San Diego, CA (US);
Assignee:
University of California San Diego, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 2/102 ; C12N 1/563 ; C07K 1/400 ;
U.S. Cl.
CPC ...
C07H 2/102 ; C12N 1/563 ; C07K 1/400 ;
Abstract
A potent peptide inhibitor (SuperSog) of TGF-&bgr; family growth factor signalling, peptide variants thereof and nucleotide coding sequences therefor are provided by the invention. The Super-Sog peptide comprises a fragment of the Drosophilia short gastrulation (Sog) gene which includes the CR-1 cysteine-rich repeat of Sog. Methods and compositions for use of Super-Sog in therapeutic and diagnostic applications are also provided.