The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2004
Filed:
Feb. 15, 1999
Applicant:
Inventors:
Andrea Dessen, Grenoble, FR;
William S. Somers, Cambridge, MA (US);
Mark L. Stahl, Lexington, MA (US);
Jasbir S. Seehra, Lexington, MA (US);
Assignee:
Genetics Institute, LLC, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06F 9/455 ; C12Q 1/44 ;
U.S. Cl.
CPC ...
G06F 9/455 ; C12Q 1/44 ;
Abstract
The present invention provides for crystalline cPLA2. The crystal structure of cPLA2 has also been solved using such material. Models based upon such crystal structure are also provided. Methods of identifying inhibitors of cPLA2 activity and membrane binding using such models are also disclosed.