The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2004
Filed:
Mar. 24, 2004
Jan Axelsson, Storvreta, SE;
Amersham Biosciences AB, Uppsala, SE;
Abstract
A micro-channel plate (MCP) detector system ( ) comprising a MCP detector, a data acquisition unit ( ), wherein the detector comprises a first and a second MCP electron multiplier ( ), one or more anodes ( ) connected to the data acquisition unit ( ) and a gate electrode ( ) disposed between the first and the second MCP electron multiplier ( ), wherein the detector system further comprises a data storage unit ( ) and a gain control unit ( ) which is connected to the gate electrode ( ) and to the data storage unit ( ), wherein a pilot spectrum is stored in the data storage unit ( ), and wherein the gain control unit ( ) is arranged to read the pilot spectrum from the data storage unit ( ), and to control the potential on the gate electrode ( ) as a function of m/z or time in response to said pilot spectrum, such that the transmission of electrons to the second MCP electron multiplier ( ) is lowered when abundant protein ions appear, whereby a high sensitivity is maintained during the remainder of the measurement cycle such that neighboring peaks from rare protein ions become detectable.