The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 05, 2004

Filed:

Jun. 07, 1995
Applicant:
Inventors:

Brian C. Cunningham, Piedmont, CA (US);

James A. Wells, Burlingame, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/827 ; C07K 1/461 ; C07K 1/4475 ;
U.S. Cl.
CPC ...
A61K 3/827 ; C07K 1/461 ; C07K 1/4475 ;
Abstract

Growth hormones contain two receptor binding sites termed site 1 and site 2 with which they form ternary complexes with their receptors. In this scheme, site 1 on the hormone binds to one molecule of receptor and then site 2 binds to another molecule of receptor, thereby producing a 1:2 complex. Disclosed herein are growth hormone variants consisting of modifications to the native sequence in the region of site 1 or site 2, or alternatively a combination of modifications at both site 1 and site 2.


Find Patent Forward Citations

Cunningham, Brian. (2004). Variants of native growth hormones having non naturally occurring amino acid sequences or covalent modifications (U.S. Patent No. 6800740). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6800740

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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