The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2004
Filed:
Apr. 11, 2001
Applicant:
Inventors:
Adrian Whitty, Hopkinton, MA (US);
Laura Runkel, Cambridge, MA (US);
Margot Brickelmaier, Boxford, MA (US);
Paula Hochman, Newton, MA (US);
Assignee:
Biogen, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 1/700 ; C12P 2/108 ; A61K 3/821 ; A61K 3/174 ;
U.S. Cl.
CPC ...
C07K 1/700 ; C12P 2/108 ; A61K 3/821 ; A61K 3/174 ;
Abstract
A fusion polypeptide is described having the amino acid sequence X-Y-Z, or portion thereof, comprising the amino acid sequence of a glycosylated interferon-beta (X); Y is an optional linker moiety; and Z is a polypeptide comprising at least a portion of a polypeptide other than glycosylated interferon-beta. It is preferred that X is human interferon-beta-1a. Mutants of interferon-beta-1a are also described.