The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 05, 2004

Filed:

Oct. 09, 2002
Applicant:
Inventors:

Douglas C. Boyes, Chapel Hill, NC (US);

Keith R. Davis, Durham, NC (US);

Jeffrey P. Woessner, Hillsborough, NC (US);

Jörn Görlach, Durham, NC (US);

Carol M. Hamilton, Morrisville, NC (US);

Neil E. Hoffman, Chapel Hill, NC (US);

Andreas S. Klöti, Durham, NC (US);

Adel Zayed, Durham, NC (US);

Robert A. Ascenzi, Cary, NC (US);

Assignee:

Paradigm Genetics, Inc., Research Triangle Park, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 2/106 ; C12N 9/00 ; C12N 1/20 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12N 2/106 ; C12N 9/00 ; C12N 1/20 ; C07H 2/104 ;
Abstract

The present inventors have discovered that chorismate mutase and chorismate synthase are essential for plant growth. Specifically, the inhibition of chorismate mutase or chorismate synthase gene expression in plant seedlings results in severe chlorosis, reduced growth and developmental abnormalities. The inventors have proven that chorismate synthase and chorismate mutase can be used as targets for the identification of herbicides. Thus, the invention provides methods for the identification of chemicals that modulate chorismate synthase and chorismate mutase biochemical reactions. The methods of the invention are useful for the identification of herbicides and for the inhibition of plant growth and development.


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