The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2004
Filed:
Aug. 28, 2001
Applicant:
Inventors:
Harry S. Nick, Gainesville, FL (US);
Richard Rogers, Gainesville, FL (US);
John F. Valentine, Gainesville, FL (US);
Assignee:
University of Florida, Gainesville, FL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/500 ; C12N 1/509 ; C12N 1/586 ; C07H 2/104 ; C12P 2/106 ;
U.S. Cl.
CPC ...
C12N 1/500 ; C12N 1/509 ; C12N 1/586 ; C07H 2/104 ; C12P 2/106 ;
Abstract
A novel transcriptional regulatory element which was isolated from the MnSOD gene and which exhibits promoter-enhancer activity is disclosed. The promoter-enhancer activity of the element is further modulated by inflammatory mediators to regulate transcription. Methods of using the promoter-enhancer element to regulate gene expression, and therapeutic uses involving the promoter-enhancer element are also described.