The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 05, 2004

Filed:

Aug. 19, 1999
Applicant:
Inventors:

Bradley B. Olwin, Boulder, CO (US);

Richard Scott Rosenthal, Raleigh, NC (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/900 ; A61K 3/818 ; A61K 3/824 ; C07K 1/00 ;
U.S. Cl.
CPC ...
A61K 3/900 ; A61K 3/818 ; A61K 3/824 ; C07K 1/00 ;
Abstract

A chimeric fibroblast growth factor protein and recombinant nucleic acid molecule encoding the same are disclosed. The chimeric fibroblast growth factor protein is characterized by: fibroblast growth factor biological activity in the absence of heparan sulfate and, entry into a living cell in the absence of a receptor that binds to FGF. Also disclosed are a method of making the chimeric fibroblast growth factor protein and methods of using the chimeric fibroblast growth factor protein to promote fibroblast growth factor activity in a cell and to enhance a biological process associated with fibroblast growth factor activity.


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