The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 28, 2004
Filed:
Mar. 13, 2001
Applicant:
Inventors:
Assignee:
York University, Toronto, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 3/350 ; G01N 3/348 ; B01D 5/944 ;
U.S. Cl.
CPC ...
G01N 3/350 ; G01N 3/348 ; B01D 5/944 ;
Abstract
A strategy for semiautomatic sequencing of argentinated (silver-containing) oligopeptides is described. The method of sequencing described is based on a search algorithm that identifies a triplet peak relationship in a product ion spectrum of the [M+Ag] ion of an oligopeptide. The ions that constitute a triplet are [b +OH+Ag] , [b −H+Ag] , and [a −H+Ag] , which are separated by 18 and 28 m/z units, respectively. The difference in the m/z values of adjacent triplets identifies the residue that is “cleaved”. Observation of the [y +H+Ag] ion containing the cleaved residue confirms the assignment.