The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 28, 2004
Filed:
Sep. 28, 2001
Applicant:
Inventors:
Sybille Marie Hunt, Epping, AU;
Peter Philip Gray, Edgecliff, AU;
Merilyn Joy Sleigh, Neutral Bay, AU;
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/06 ; C12N 5/10 ;
U.S. Cl.
CPC ...
C12N 5/06 ; C12N 5/10 ;
Abstract
Methods of production of desired recombinant proteins, polypeptides and peptides are disclosed which utilize mammalian host cells engineered for autonomous and regulated growth in low cost protein/serum-free culture media. Preferred host cells express insulin or an insulin-like growth factor, and/or transferrin and are engineered so that addition of an inducer (e.g., ZnCl +CdCl ) halts growth and simultaneously induces the expression of the desired recombinant protein, polypeptide or peptide.