The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 21, 2004

Filed:

Oct. 09, 2002
Applicant:
Inventors:

Wilhelmus Hubertus Joseph Boesten, Sittard, NL;

Harold Monro Moody, Maastricht, NL;

Bernardus Kaptein, Sittard, NL;

Johannes Paulus Gerardus Seerden, Groningen, NL;

Marcelles Van Der Sluis, Groningen, NL;

Ben Lange De, Munstergeleen, NL;

Quirinus Bernardus Broxterman, Munstergeleen, NL;

Assignee:

DSM N.V., Te Heerlen, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ;
U.S. Cl.
CPC ...
C07C / ;
Abstract

Process for the preparation of a diasteromerically enriched phenylglycine amide derivative in which an enantiomerically enriched phenylglycine amide is converted into the corresponding Schiff base with the aid of compound R —C(O)—R , and the Schiff base obtained is subsequently converted into the diastereomerically enriched phenyglycine amide derivative with the aid of a cyanide source, a reducing agent or an allyl organometallic compound. The phenylglycine amide derivatives obtained are interesting starting materials for the preparation of for example enantiomerically enriched &agr;- and or &bgr;-amino acids and derivatives thereof, such as amides and esters, and amines.


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