The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 21, 2004
Filed:
Aug. 07, 2000
Applicant:
Inventors:
Gerard Andrew Potter, Leicester, GB;
Lawrence Hylton Patterson, Leicester, GB;
Michael Danny Burke, Leicester, GB;
Assignee:
De Montfort University, Leicester, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C / ; C07D / ; A61K 3/127 ; A61P 3/500 ;
U.S. Cl.
CPC ...
C07C / ; C07D / ; A61K 3/127 ; A61P 3/500 ;
Abstract
The present invention concerns prodrugs whose aromatic oxidation, particularly their enzymatic aromatic hydroxylation, results in their activation by the release of a drug moiety. It particularly concerns anti-tumor prodrugs and those which are specifically activated by the hydroxylation activity of the P-450 enzyme CYP1B1. Also provided are methods of detection of aromatic oxidation activity.
Potter, Gerard. (2004). Hydroxylation activated drug release (U.S. Patent No. 6794384). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6794384
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile