The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 14, 2004

Filed:

Sep. 12, 2001
Applicant:
Inventors:

Marek Kwiatkowski, Uppsala, SE;

Ulf Landegren, Uppsala, SE;

Mats Nilsson, Uppsala, SE;

Assignee:

Quiatech AB, , SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 2/104 ; C07H 2/102 ; C12Q 1/68 ; C12M 1/36 ;
U.S. Cl.
CPC ...
C07H 2/104 ; C07H 2/102 ; C12Q 1/68 ; C12M 1/36 ;
Abstract

A method of preparing an immobilized oligonucleotide having a free 3′-end comprises the steps of: i) preparing an oligonucleotide attached in a first position to a solid support via its 3′-end and having a free 5′-end; ii) binding said oligonucleotide in a second position remote from the 3′-end to the solid support; and iii) selectively releasing the 3′-end of the oligonucleotide from the solid support to obta the oligonucleotide attached to the support in said second position in a reversed orientation with a free 3′-end.


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