The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2004
Filed:
Jun. 27, 2001
Applicant:
Inventors:
Mark E. Gurney, Grand Rapids, MI (US);
Michael J. Bienkowski, Portage, MI (US);
Robert L. Heinrikson, Plainwell, MI (US);
Luis A. Parodi, Stockholm, SE;
Riqiang Yan, Kalamazoo, MI (US);
Assignee:
Pharmacia & Upjohn Company, Kalamazoo, MI (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/00 ; C12Q 1/25 ; C07K 1/400 ;
U.S. Cl.
CPC ...
C12Q 1/00 ; C12Q 1/25 ; C07K 1/400 ;
Abstract
The present invention provides the enzyme and enzymatic procedures for cleaving the &bgr; secretase cleavage site of the APP protein and associated nucleic acids, peptides, vectors, cells and cell isolates and assays. The invention further provides a modified APP protein and associated nucleic acids, peptides, vectors, cells, and cell isolates, and assays that are particularly useful for identifying candidate therapeutics for treatment or prevention of Alzheimer's disease.