The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 2004
Filed:
Aug. 03, 2000
Applicant:
Inventors:
Alberto A. Gabizon, Jerusalem, IL;
Eliezer Kedar, Jerusalem, IL;
Yechezkel Barenholz, Jerusalem, IL;
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/819 ; A61K 3/820 ; A61K 3/821 ; C07B / ;
U.S. Cl.
CPC ...
A61K 3/819 ; A61K 3/820 ; A61K 3/821 ; C07B / ;
Abstract
A method of antitumor therapy is described in which administration of a chemotherapeutic drug, encapsulated in liposomes, is supplemented by administration of an immunostimulating cytokine. The cytokine is preferably also encapsulated in liposomes. In tumor models for lung and colon carcinomas, this method produced a significantly greater therapeutic effect, as evidenced by survival rate and tumor size, than a combination of the effects produced by the free or liposome-encapsulated components administered individually.