The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 31, 2004

Filed:

Feb. 09, 2001
Applicant:
Inventors:

Richard H. Peters, San Jose, CA (US);

Jyanwei Liu, Sunnyvale, CA (US);

John G. Johansson, Menlo Park, CA (US);

Kenneth J. Ryan, Sunnyvale, CA (US);

Wan-Ru Chao, Sunnyvale, CA (US);

Masato Tanabe, Palo Alto, CA (US);

Assignee:

SRI International, Menlo Park, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/156 ; C07J 5/00 ; C07J 7/00 ; C07J 4/300 ;
U.S. Cl.
CPC ...
A61K 3/156 ; C07J 5/00 ; C07J 7/00 ; C07J 4/300 ;
Abstract

Syntheses of steroids such as 3-hydroxy-7&agr;-methyl-21-[2′-methoxy-4′-(diethylaminomethyl)-phenoxy]-19-norpregna-1,3,5(10)triene citrate (“SR 16234”) and analogs thereof are provided, wherein 21-hydroxy-19-norpregna-4-en-3-one serves as a starting material or intermediate. The latter compound may be readily prepared from estrone-3-methyl ether. Certain intermediates in these syntheses also have value as therapeutic agents, for example in the treatment of prostate disorders such as prostatic cancer.


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