The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 24, 2004
Filed:
Oct. 15, 2001
Yih-Tai Chen, Gibsonia, PA (US);
Longguang Cao, Boulder, CO (US);
Cellomics, Inc., Pittsburgh, PA (US);
Abstract
Synthetic versions of a full length and termini truncated humanized green fluorescent protein based on are disclosed which have been modified to the favored or most favored codons for mammalian expression systems. The disclosed encoded protein has 239 amino acid residues compared with the wild type which has 238 amino acids. In the present invention, a valine residue has been added at the second position from the amino terminus and codon preference bias has been changed in a majority of the wild type codons of fluorescent protein. The humanized green fluorescent protein is useful as a fluorescent tag for monitoring the activities of its fusion partners using imaging based approaches.