The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 24, 2004

Filed:

Sep. 27, 2001
Applicant:
Inventors:

Kazuo Kondo, Tokyo, JP;

Osamu Igarashi, Tokyo, JP;

Chikako Kiyose, Saitama, JP;

Hiroyuki Yoshimura, Ibaraki, JP;

Shigehiro Yoshitake, Nara, JP;

Assignee:

Eisai Co., Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1352 ; A61P 9/10 ;
U.S. Cl.
CPC ...
A61K 3/1352 ; A61P 9/10 ;
Abstract

The present invention provides a method of preventing or treating a disease caused by oxidation in vivo by administering a pharmacologically effective amount of at least one compound selected from the group consisting of: (1) 2,5,7,8-tetramethyl-2-(&bgr;-carboxyethyl)-6-hydroxychromane; and (2) 2,7, 8-trimethyl-2-(&bgr;-carboxyethyl)-6-hydroxychromane. Further, it provides use of a compound selected from the group consisting of (3) &agr;-tocopherol, (4) &agr;-tocotrienol, (5) &ggr;-tocopherol and (6) &ggr;-tocotrienol for generation in vivo of any of the above compounds (1) and (2) to treat a disease caused by oxidated low density lipoprotein (LDL).


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