The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 24, 2004
Filed:
Sep. 09, 1997
Applicant:
Inventors:
Jean Haensler, St. Genis-les-Ollières, FR;
Emmanuelle Trannoy, Lyons, FR;
Jorge Ronco, Lyons, FR;
Assignee:
Aventis Pasteur SA, Lyons, FR;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 4/500 ; A61K 3/800 ; A61K 3/900 ; A61K 3/9145 ;
U.S. Cl.
CPC ...
A61K 4/500 ; A61K 3/800 ; A61K 3/900 ; A61K 3/9145 ;
Abstract
An amphipathic compound including a sterol-derived lipophilic grouping bound to a cationic grouping for use as an adjuvant in the delivery of a vaccine composition. In a particular embodiment, the lipophilic grouping is a cholesterol derivative and the cationic grouping is a quaternary ammonium or a protonatable amine. A vaccine composition including one or more antigens with at least one amphipathic compound having a sterol-derived lipophilic grouping bound to a cationic grouping, is also disclosed.