The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 24, 2004
Filed:
Sep. 15, 2000
Applicant:
Inventors:
Enzo Paoletti, Delmar, NY (US);
James Tartaglia, Schenectady, NY (US);
William I. Cox, Troy, NY (US);
Assignee:
Aventis Pasteur, Swiftwater, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 6/300 ; A61K 4/800 ; A61K 3/9100 ; C12N 1/500 ;
U.S. Cl.
CPC ...
A01N 6/300 ; A61K 4/800 ; A61K 3/9100 ; C12N 1/500 ;
Abstract
Attenutated recombinant viruses containing DNA coding for a cytokine and/or a tumor associated antigen, as well as methods and compositions employing the viruses, are disclosed and claimed. The recombinant viruses can be NYVAC or ALVAC recombinant viruses. The DNA can code for at least one of: human tumor necrosis factor; nuclear phosphoprotein p53, wiltype or mutant; human melanoma-associated antigen; IL-2; IFN&ggr;; IL-4; GMCSF; IL-12; B7; erb-B-2 and carcinoembryonic antigen. The recombinant viruses and gene products therefrom are useful for cancer therapy.