The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6777552 B1

PDF
Full Text
Expired
Date of Patent:
Aug. 17, 2004

Filed:

Aug. 16, 2002
Applicant:
Inventors:

Valerie Niddam-Hildesheim, Even-Yeouda, IL;

Revital Lifshitz-Liron, Herzlia, IL;

Rami Lidor-Hadas, Kafar-Saba, IL;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; C07D / ;
Abstract

Processes for preparing a calcium salt of a statin from an ester derivative or protected ester derivative of the statin by using calcium hydroxide are provided. The ester or protected ester derivative is contacted with calcium hydroxide to obtain the calcium salt. Preferred statins are rosuvastatin, pitavastatin and atorvastatin, simvastatin and lovastatin. In processes beginning with a protected statin ester derivative, the protecting group is hydrolyzed during salt formation by contact with calcium hydroxide, or is contacted with an acid catalyst followed by contact with calcium hydroxide.


Find Patent Forward Citations

Niddam-Hildesheim, Valerie. (2004). Processes for preparing calcium salt forms of statins (U.S. Patent No. 6777552). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6777552

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