The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 17, 2004
Filed:
Jan. 28, 2002
Johannes Gerdes, Feldhorst, DE;
Thomas Scholzen, Neritz, DE;
Elmar Endi, Hamburg, DE;
Claudia Wohlenberg, Hamburg, DE;
Bettina Baron-Lühr, Bad Segeberg, DE;
Margrit Kernbach Hahn, Kaltenkirchen, DE;
Patricia Prilla, Borstal, DE;
Johanna Suwinski, Wiemersdorf, DE;
Rolf Knippers, Konstanz, DE;
Dakocytomation Denmark A/S, Glostrup, DK;
Abstract
The present invention relates to monoclonal antibodies against the human Mcm3 protein, hybridoma cell lines that produce such antibodies, procedures for the production and their use, pharmaceutical compositions comprising a monoclonal antibody according to the present invention, their use for the prevention and treating of certain diseases as well as methods relating to the prevention and treatment of diseases associated with Mcm3 expression. Monoclonal antibodies according to the invention detect and bind human Mcm3 monospecifically both in immunohistological and immunobiochemical detection systems. The process for the production of these monoclonal antibodies comprises an initial screening of excess hybridoma supernatant with immunobiochemical methods followed by a second screening of positive hybridoma by means of an immunohistochemical method.