The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 10, 2004
Filed:
Aug. 31, 1990
Applicant:
Inventors:
David Parker, Durham, GB;
Thomas Andrew Millican, Maidenhead, GB;
Assignee:
Celltech Limited, Berkshire, GB;
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07F 1/06 ; C07F 5/00 ; A61B 5/055 ;
U.S. Cl.
CPC ...
C07D / ; C07F 1/06 ; C07F 5/00 ; A61B 5/055 ;
Abstract
1,4,7,10-Tetrazacyclododecanes carrying a side chain terminating in a group capable of reacting with an antibody, and their complexes with a di- or tripositive metal having a coordination number of 6 or more can be used to prepare imaging agents. Typical metals are indium, copper, lead, bismuth, yttrium, terbium, gadolinium, and scandium. The compounds can be reacted with a monoclonal or polyclonal antibody or antibody fragment to target the metal to a specific type of tissue.