The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 10, 2004

Filed:

Nov. 03, 1997
Applicant:
Inventors:

Gunnar Norstedt, Bromma, SE;

Tim Wood, Stockholm, SE;

Daniel Sliva, Stockholm, SE;

Bertil Enberg, Grödinge, SE;

Peter Lobie, Bandhagen, SE;

Lars-Arne Haldosen, Rönninge, SE;

Assignee:

Biovitrum AB, Stockholm, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 2/104 ; C12N 5/00 ; C12N 1/500 ; C12N 1/509 ; C12N 1/563 ;
U.S. Cl.
CPC ...
C07H 2/104 ; C12N 5/00 ; C12N 1/500 ; C12N 1/509 ; C12N 1/563 ;
Abstract

A method of enhancing the transcription of a gene in a DNA construct incorporated into the genome of a eucaryotic host cell, wherein the DNA construct comprises a structural gene for a desired protein or polypeptide in a gene promoter upstream of the structural gene, comprises providing at least one enhancer element comprising the nucleotide sequence TTC TGA GAA upstream of the promoter, and exposing the DNA construct to lactogenic stimuli. An expression vector, a host cell and a transgenic mammal containing the vector are of interest.


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