The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 2004
Filed:
Mar. 07, 2002
Applicant:
Inventors:
Jan Domin, London, GB;
Michael Derek Waterfield, London, GB;
Assignee:
Ludwig Institute for Cancer Research, Zurich, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 ; C12N 1/20 ; C12N 1/500 ; C12N 5/00 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12N 9/12 ; C12N 1/20 ; C12N 1/500 ; C12N 5/00 ; C07H 2/104 ;
Abstract
A novel human class II PI3 kinase including the sequence of the isolated nucleic acid molecule which encodes the kinase and the encoded amino acid sequence. The new human PI3 kinase is termed PI3K-C2&agr; and has unique biochemical properties that characterize it and distinguish it from previously known PI3 kinases. These include, among other things, resistance to the PI3 kinase inhibitors Wortmannin and LY294000, the lack of a p85 binding site, a divergent amino terminus, and the absence of a polyproline motif which is typical of previously known type II PI3 kinases.