The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 03, 2004

Filed:

Jun. 25, 2001
Applicant:
Inventors:

Lynette B. Corbeil, San Diego, CA (US);

Elizabeth J. Ziegler, San Diego, CA (US);

Jerry D. Sanders, Fenton, MI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 6/300 ; A01N 6/500 ;
U.S. Cl.
CPC ...
A01N 6/300 ; A01N 6/500 ;
Abstract

The present invention provides a method for protecting cattle from diseases such as septicemia, pneumonia or abortion by immunizing them with an vaccine. Provided are natural isolates of strains that have one or more important features of such vaccine, including, sensitivity to killing in complement-containing bovine serum, lack of expression of immunoglobulin binding proteins, expression of protective antigens and a reduction in the release of endotoxin during growth. Vaccines using having these and other features also can be prepared from natural isolates of asymptomatic carriers or from pathogenic organisms by recombinant DNA techniques.


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